1 INDICATIONS AND USAGE Ondansetron is indicated for the prevention of nausea and vomiting associated with: â€¢highly emetogenic cancer chemotherapy, including cisplatin greater than or equal to 50 mg/m2 â€¢initial and repeat courses of moderately emetogenic cancer chemotherapy â€¢radiotherapy in patients receiving either total body irradiation, single high-dose fraction to the abdomen, or daily fractions to the abdomen Ondansetron is also indicated for the prevention of postoperative nausea and/or vomiting. Ondansetron is a 5-HT3 receptor antagonist indicated for the prevention of: â€¢nausea and vomiting associated with highly emetogenic cancer chemotherapy, including cisplatin greater than or equal to 50 mg/m2 (1) â€¢nausea and vomiting associated with initial and repeat courses of moderately emetogenic cancer chemotherapy (1) â€¢nausea and vomiting associated with radiotherapy in patients receiving either total body irradiation, single high-dose fraction to the abdomen, or daily fractions to the abdomen (1) â€¢postoperative nausea and/or vomiting (1)
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