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INDICATIONS AND USAGE Carbidopa and levodopa tablets are indicated in the treatment of Parkinson's disease, post-encephalitic parkinsonism, and symptomatic parkinsonism that may follow carbon monoxide intoxication or manganese intoxication. Carbidopa allows patients treated for Parkinson's disease to use much lower doses of levodopa. Some patients who responded poorly to levodopa have improved on carbidopa and levodopa tablets. This is most likely due to decreased peripheral decarboxylation of levodopa caused by administration of carbidopa rather than by a primary effect of carbidopa on the nervous system. Carbidopa has not been shown to enhance the intrinsic efficacy of levodopa. Carbidopa may also reduce nausea and vomiting and permit more rapid titration of levodopa.
sciegen pharmaceuticals inc
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HOW SUPPLIED
CARBIDOPA AND LEVODOPA tablets, USP 10 mg/100 mg are light blue, mottled, round, uncoated tablets debossed with 'SG' on one side and ‘457' on the other. They are supplied as follows: Bottle of 30's NDC 50228-457-30 Bottle of 100's NDC 50228-457-01 Bottle of 500's NDC 50228-457-05 Bottle of 1000's NDC 50228-457-10
CARBIDOPA AND LEVODOPA tablets, USP 25 mg/100 mg are light yellow, mottled, round, uncoated tablets debossed with 'SG' on one side and ‘458' on the other. They are supplied as follows: Bottle of 30's NDC 50228-458-30 Bottle of 100's NDC 50228-458-01 Bottle of 500's NDC 50228-458-05 Bottle of 1000's NDC 50228-458-10
CARBIDOPA AND LEVODOPA tablets, USP 25 mg/250 mg are light blue, mottled, round, uncoated tablets debossed with 'SG' on one side and ‘459' on the other. They are supplied as follows: Bottle of 30's NDC 50228-459-30 Bottle of 100's NDC 50228-459-01 Bottle of 500's NDC 50228-459-05 Bottle of 1000's NDC 50228-459-10 Storage and Handling Store at 20° to 25°C (68° to 77°F), excursions permitted to 15° to 30°C (59° to 86°F) [see USP Controlled Room Temperature]. Store in a tightly closed container, protected from light and moisture. Dispense in a tightly closed, light-resistant container. Manufactured by: ScieGen Pharmaceuticals, Inc. Hauppauge, NY 11788 Rev. 5/2021
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