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lisinopril tablet 40 mg

1 INDICATIONS AND USAGE Lisinopril is an angiotensin converting enzyme (ACE) inhibitor indicated for: Treatment of hypertension in adults and pediatric patients 6 years of age and older ( 1.1 ) Adjunct therapy for heart failure ( 1.2 ) Treatment of Acute Myocardial Infarction ( 1.3 ) 1.1 hypertension Lisinopril tablets are indicated for the treatment of hypertension in adult patients and pediatric patients 6 years of age and older to lower blood pressure. Lowering blood pressure lowers the risk of fatal and non-fatal cardiovascular events, primarily strokes and myocardial infarctions. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes. Control of high blood pressure should be part of comprehensive cardiovascular risk management, including, as appropriate, lipid control, diabetes management, antithrombotic therapy, smoking cessation, exercise, and limited sodium intake. Many patients will require more than 1 drug to achieve blood pressure goals. For specific advice on goals and management, see published guidelines, such as those of the National High Blood Pressure Education Program’s Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC). Numerous antihypertensive drugs, from a variety of pharmacologic classes and with different mechanisms of action, have been shown in randomized controlled trials to reduce cardiovascular morbidity and mortality, and it can be concluded that it is blood pressure reduction, and not some other pharmacologic property of the drugs, that is largely responsible for those benefits. The largest and most consistent cardiovascular outcome benefit has been a reduction in the risk of stroke, but reductions in myocardial infarction and cardiovascular mortality also have been seen regularly. Elevated systolic or diastolic pressure causes increased cardiovascular risk, and the absolute risk increase per mmHg is greater at higher blood pressures, so that even modest reductions of severe hypertension can provide substantial benefit. Relative risk reduction from blood pressure reduction is similar across populations with varying absolute risk, so the absolute benefit is greater in patients who are at higher risk independent of their hypertension (for example, patients with diabetes or hyperlipidemia), and such patients would be expected to benefit from more aggressive treatment to a lower blood pressure goal. Some antihypertensive drugs have smaller blood pressure effects (as monotherapy) in Black patients, and many antihypertensive drugs have additional approved indications and effects (e.g., on angina, heart failure, or diabetic kidney disease). These considerations may guide selection of therapy. Lisinopril tablets may be administered alone or with other antihypertensive agents [see Clinical Studies (14.1) ]. 1.2 heart failure Lisinopril tablets are indicated to reduce signs and symptoms of systolic heart failure [see Clinical Studies (14.2) ] . 1.3 Reduction of Mortality in Acute Myocardial Infarction Lisinopril tablets are indicated for the reduction of mortality in treatment of hemodynamically stable patients within 24 hours of Acute Myocardial Infarction. Patients should receive, as appropriate, the standard recommended treatments such as thrombolytics, aspirin and beta-blockers [see Clinical Studies (14.3) ] .

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2 days ago OVAL WHITE V 42 10 lisinopril tablet 40 mg

OVAL WHITE V 42 10

2 days ago OVAL WHITE V 42 10 lisinopril tablet 40 mg

V 42 10 OVAL WHITE

16 HOW SUPPLIED/STORAGE AND HANDLING Lisinopril Tablets, USP 2.5 mg are white, oval shaped, convex tablets, debossed β€œ4209” on one side and β€œV” on the reverse side; and supplied as follows: Bottles of 100: NDC 0603-4209-21 Bottles of 500: NDC 0603-4209-28 Lisinopril Tablets, USP 5 mg are white, capsule shaped, convex, bisected tablets, debossed β€œ42/10” on one side and β€œV” on the reverse side; and supplied as follows: Bottles of 30: NDC 0603-4210-16 Bottles of 45: NDC 0603-4210-60 Bottles of 90: NDC 0603-4210-02 Bottles of 100: NDC 0603-4210-21 Bottles of 500: NDC 0603-4210-28 Bottles of 1000: NDC 0603-4210-32 Bottles of 2500: NDC 0603-4210-30 Lisinopril Tablets, USP 10 mg are white, round, convex tablets, debossed β€œ3972” on one side and β€œV” on the reverse side; and supplied as follows: Bottles of 45: NDC 0603-4211-60 Bottles of 90: NDC 0603-4211-02 Bottles of 100: NDC 0603-4211-21 Bottles of 500: NDC 0603-4211-28 Bottles of 1000: NDC 0603-4211-32 Bottles of 5000: NDC 0603-4211-34 Lisinopril Tablets, USP 20 mg are white, round, convex tablets, debossed β€œ3973” on one side and β€œV” on the reverse side; and supplied as follows: Bottles of 45: NDC 0603-4212-60 Bottles of 90: NDC 0603-4212-02 Bottles of 100: NDC 0603-4212-21 Bottles of 500: NDC 0603-4212-28 Bottles of 1000: NDC 0603-4212-32 Bottles of 5000: NDC 0603-4212-34 Lisinopril Tablets, USP 30 mg are white, round, convex tablets, debossed β€œ3974” on one side and β€œV” on the reverse side; and supplied as follows: Bottles of 100: NDC 0603-4213-21 Bottles of 500: NDC 0603-4213-28 Lisinopril Tablets, USP 40 mg are white, round, convex tablets, debossed β€œ4214” on one side and β€œV” on the reverse side; and supplied as follows: Bottles of 45: NDC 0603-4214-60 Bottles of 90: NDC 0603-4214-02 Bottles of 100: NDC 0603-4214-21 Bottles of 180: NDC 0603-4214-04 Bottles of 500: NDC 0603-4214-28 Bottles of 1000: NDC 0603-4214-32 Bottles of 2500: NDC 0603-4214-30 Store at 20Β° to 25Β°C (68Β° to 77Β°F) [see USP Controlled Room Temperature]. Protect from moisture, freezing and excessive heat. Dispense in a tight container.


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